Does having a child affected by AADC Deficiency affect our decision to have more children?

Yes probably...

If you have a child affected by AADC deficiency, this may influence your decision for more children. 

If the parents have another child there is a 25% chance that the child will be affected by AADC deficiency, a 50% chance that the child will be a heterozygote carrier and a 25% chance that the child will have a completely normal AADC gene. See ‘is AADC an inherited disease’ for more information.

It is not always possible to pinpoint the exact location of the mutated allele on the AADC gene even after a child has a confirmed diagnosis of AADC deficiency. If the mutation(s) have been located in your affected child, pre-natal diagnosis may be possible. Please consult with your physician and genetic counsellor.